Ontology Infrastructure
Every concept, every code, every relationship.
TICH's ontology layer normalizes every disease, symptom, pathogen, medicine, adverse event and intervention against six global standards. The same engine powers semantic search, the knowledge graph, AI grounding and regulatory cross-walks.
Indexed concepts
2.4M
Standards
6
Cross-walks
11.8M
Updated
Daily
Diabetes mellitusSGLT2 inhibitorsFournier's gangrenePlasmodium falciparumCarbapenem resistance
Clinical terminology
SNOMED CT
352,000+ concepts indexed
Cross-walked to all 5 sibling standards
Diseases & conditions
ICD-11
55,000+ concepts indexed
Cross-walked to all 5 sibling standards
Adverse events
MedDRA
84,000+ concepts indexed
Cross-walked to all 5 sibling standards
Medications & ingredients
RxNorm
270,000+ concepts indexed
Cross-walked to all 5 sibling standards
Biomedical literature
MeSH
30,000+ concepts indexed
Cross-walked to all 5 sibling standards
Drug classification
ATC
6,400+ concepts indexed
Cross-walked to all 5 sibling standards
Sample concept resolution
Entity graph · live cross-walks
SNOMED CT73211009
Diabetes mellitus (disorder)
Semantic type · Disease or Syndrome
DMDiabetes
Related entities
- treated_byMetforminRxNorm 6809
- guidelineADA Standards of Care 2025TICH-GL
- icd115A11 · Type 2 diabetes mellitusICD-11
- complicationDiabetic ketoacidosisSNOMED 420422005
MedDRA PT10019805
Fournier's gangrene
Semantic type · Adverse event
Necrotizing fasciitis of perineum
Related entities
- signal_forSGLT2 inhibitorsATC A10BK
- regulatorEMA PRAC 2026-117EMA
- ror4.2 (3.1–5.7) EudraVigilancePV
ATCA10BJ
Glucagon-like peptide-1 (GLP-1) analogues
Semantic type · Pharmacologic class
GLP-1 receptor agonists
Related entities
- memberSemaglutideRxNorm 1991302
- indicationType 2 diabetes mellitusICD-11 5A11
- outcomeReduces 3-point MACE (HR 0.86)TICH evidence
AI grounding
Every TICH AI answer resolves named entities against this ontology layer before generating a response.
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Pharmacovigilance coding
ADR reports are MedDRA-coded automatically and cross-walked to RxNorm and ATC for signal detection.
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Guideline cross-walks
WHO, NICE and ESC guideline statements are indexed by SNOMED CT and ICD-11 for instant comparison.
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